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Image Blood in the abdominal cavity
Blood or blood-stained fluid in the abdomen is one of the macroscopic signs of RHD although it is not diagnostic. Differential diagnoses include trauma, ruptured tumours, and end-stage hepatic lipidosis where the liver is so friable that it splits and bleeds. This case was confirmed as RHD.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image Blood-stained fluid at nares
Blood-stained fluid in the nares may be seen in rabbits that have died suddenly from RHD. A foamy blood-stained exudate in the trachea is a feature of the diseases and the exudate may extend to the nostrils
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image ECMAScript program Ecchymotic pulmonary haemorrhages
In this confirmed case of RHD, ecchymotic haemorrhages were evident macroscopically and alveolar haemorrhages were seen microscopically.
Located in Media / … / MACROSCOPIC CHANGES / LUNGS
Image Enlarged congested liver
An enlarged congested liver can be due to rabbit haemorrhagic disease (RHD) but is also a macroscopic feature of other conditions, such as congestive heart failure or septicaemia. Close inspection of the liver shows a mottled appearance, which is suggestive of RHD. In this case, RHD was diagnosed from the histopathological finding of characteristic hepatocellular necrosis.
Located in Media / … / MACROSCOPIC CHANGES / LIVER
Image Enlarged pale, mottled liver
The liver is always affected in rabbits with RHD. Microscopically hepatocellular necrosis is present in all cases. Macroscopically, there may be minimal changes or hepatomegaly with a pale mottled appearance as in this rabbit that died from RHDV2 confirmed by PCR testing.
Located in Media / … / MACROSCOPIC CHANGES / LIVER
Image JPEG image Enlarged, congested, mottled liver
Congestion is often present in the organs of rabbits that have died from RHD and can mask other characteristic changes. The liver of this rabbit that died from RHD is congested. Close inspection shows a mottled appearance.
Located in Media / … / MACROSCOPIC CHANGES / LIVER
Image JPEG image Kidney
The kidney is frequently affected by RHD. Histologically, glomerular thrombosis is a feature of the disease in many cases. Macroscopic changes are often masked by congestion, so the kidney is dark red, which was the case in this rabbit that died from RHD. Manipulation of the image (shadow and highlight) has shown that changes were present.
Located in Media / … / MACROSCOPIC CHANGES / KIDNEY
Image image/x-jg Myocardial haemorrhages
Disseminated intravascular coagulopathy is a feature of acute cases of RHD and haemorrhages may be found in any part of the body. In this case, there were multifocal areas of haemorrhage in the myocardium, which were evident macroscopically and microscopically.
Located in Media / … / MACROSCOPIC CHANGES / HEART
Image Octet Stream Pulmonary congestion and oedema
Pulmonary haemorrhage and oedema are features of RHD although, macroscopically, it can be difficult to differentiate agonal changes, such as alveolar collapse, congestion, and alveolar oedema from lung pathology. In this confirmed case of RHD, fibrin thrombi were seen in occasional small capillaries and venules on histopathological examination.
Located in Media / … / MACROSCOPIC CHANGES / LUNGS
Image Rabbit Haemorrhagic Disease
This half-grown female wild rabbit was found dead. There were no signs of external injury. Post-mortem examination revealed a full gastrointestinal tract - the rabbit had been eating up until an hour or two before death. The liver was enlarged and mottled, the lungs contained several haemorrhages in addition to a pale, necrotic area in the left caudal lung lobe. Histopathology showed the characteristic hepatocellular necrosis of RHD. The pale area in the lung was an aspergilloma and there was also evidence of hepatic coccidiosis. The case was confirmed as RHDV2 with PCR testing.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION