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Image Cystic liver
Biliary cysts occasionally occur in rabbits. They are usually benign but may become calcified so they are visible on abdominal radiographs
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image Eimeria steidae
The external surface of a liver lobe from a rabbit that died with RHD2. The liver is abnormally congested with blood but a local area of white tissue is identifiable. This coauld have a number of causes so the liver lobe was cut at this level.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image Eimeria steidae
The freshly cut section of liver of a young male wild rabbit that died from RDH2, shows several areas of fibrosis involving the bile ducts. There is also a normal bile duct running across the section. This appearance is very suggestive of hepatic coccidiosis. Cytology can be used to confirm the presence of coccidial oocysts. Histology will also show the oocysts as well as showing the typical changes produced by RHD. A pcr test for rhd/rhd2 is required to confirm the presence of this viral disease.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image Eimeria steidae
Hepatic coccidia obtained by a firmly-made impression with a microscope slide onto the cut surface of an affected liver. The slide was stained with RapidDiff2. The rabbit had died from RHDV2 which made an unavoidable preponderance of erythrocytes even with careful preparation (blotting) of the liver before applying the slide. Three slides were made and this, the third, was the only slide with coccidia. Success with this technique requires careful blotting of the cut surface and some pressure on the sides of the liver so that coccidia are squeezed out of the affected bile ducts.
Located in Media / / PATHOLOGY / HISTOLOGY
Image Enlarged congested liver
An enlarged congested liver can be due to rabbit haemorrhagic disease (RHD) but is also a macroscopic feature of other conditions, such as congestive heart failure or septicaemia. Close inspection of the liver shows a mottled appearance, which is suggestive of RHD. In this case, RHD was diagnosed from the histopathological finding of characteristic hepatocellular necrosis.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image Enlarged pale, mottled liver
The liver is always affected in rabbits with RHD. Microscopically hepatocellular necrosis is present in all cases. Macroscopically, there may be minimal changes or hepatomegaly with a pale mottled appearance as in this rabbit that died from RHDV2 confirmed by PCR testing.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image JPEG image Enlarged, congested, mottled liver
Congestion is often present in the organs of rabbits that have died from RHD and can mask other characteristic changes. The liver of this rabbit that died from RHD is congested. Close inspection shows a mottled appearance.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image SIS package Hepatic coccidiosis
A low power view of hepatic coccidiosis. The rabbit died from RHD2 and this was a coincidental finding
Located in Media / / PATHOLOGY / HISTOLOGY
Image SIS package Hepatic lipidosis
Hepatic lipidosis is the end point of untreated gut stasis. Fat is broken down as an energy source and is broken down by beta-oxidation in the liver. A metabolic bottleneck occurs and ketoacidosis is the result. Affected rabbits die from liver and/or kidney failure. Disseminated intravascular coagulopathy may occur. Gastric ulceration is another feature of untreated gut stasis. This image shows the appearance of the liver and stomach of a rabbit that died from hepatic lipidosis: the liver is very pale and the dark areas on the stomach are ulcers. The primary problem was a dental spur.
Located in Media / / MACROSCOPIC CHANGES / LIVER
Image SIS package Hepatic lipidosis
This image shows the liver of a rabbit that died with hepatic lipidosis. She died a few hours after admission, despite intravenous fluids and other supportive treatment. She was ataxic and hypothermic with a low blood glucose (4.2 mmol/l) on admission. Her urine was acidic on a dipstick due to ketoacidosis. The rabbit had undergone radical dentistry at another practice 4 days earlier and had not eaten since she was discharged on the day of dentistry.
Located in Media / / MACROSCOPIC CHANGES / LIVER