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Image JPEG image Kidney
The kidney is frequently affected by RHD. Histologically, glomerular thrombosis is a feature of the disease in many cases. Macroscopic changes are often masked by congestion, so the kidney is dark red, which was the case in this rabbit that died from RHD. Manipulation of the image (shadow and highlight) has shown that changes were present.
Located in Media / … / MACROSCOPIC CHANGES / KIDNEY
Image Splenomegaly
An enlarged spleen may be seen in cases of RHD. There are few other causes of splenomegaly in this species. Histologically the changes can range from moderate congestion to haemorrhage, deposition of fibrin, lymphocytolysis and necrosis of lymphoid tissue.
Located in Media / … / MACROSCOPIC CHANGES / SPLEEN
Image JPEG image Subtle macroscopic signs of RHD
Gross post-mortem signs are not always obvious in rabbits that died from RHD and this rabbit is an example. The liver is slightly enlarged and close inspection with a hand lens did show a mottled appearance. Histopathology showed characteristic hepatocellular necrosis and PCR testing confirmed the presence of RHDV2.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image JPEG image RHD: macroscopic findings
Macroscopic abnormalities are not always obvious in rabbits that have died from RHD. Histopathology reveals severe underlying pathology in the liver, often accompanied by other organs. RHD was confirmed in this rabbit.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image Blood in the abdominal cavity
Blood or blood-stained fluid in the abdomen is one of the macroscopic signs of RHD although it is not diagnostic. Differential diagnoses include trauma, ruptured tumours, and end-stage hepatic lipidosis where the liver is so friable that it splits and bleeds. This case was confirmed as RHD.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image Rabbit Haemorrhagic Disease
This half-grown female wild rabbit was found dead. There were no signs of external injury. Post-mortem examination revealed a full gastrointestinal tract - the rabbit had been eating up until an hour or two before death. The liver was enlarged and mottled, the lungs contained several haemorrhages in addition to a pale, necrotic area in the left caudal lung lobe. Histopathology showed the characteristic hepatocellular necrosis of RHD. The pale area in the lung was an aspergilloma and there was also evidence of hepatic coccidiosis. The case was confirmed as RHDV2 with PCR testing.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image Blood-stained fluid at nares
Blood-stained fluid in the nares may be seen in rabbits that have died suddenly from RHD. A foamy blood-stained exudate in the trachea is a feature of the diseases and the exudate may extend to the nostrils
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image JPEG image RHD
This picture shows the abdominal contents of an adult lionhead neutered male rabbit that died the day after a general anaesthetic for dentistry. The liver is swollen and pale and there is haemorrhagic fluid in the abdomen. Histopathology showed characteristic signs of RHD, including hepatocellular necrosis. PCR testing confirmed the presence of RHDV2.
Located in Media / … / MACROSCOPIC CHANGES / GROSS EXAMINATION
Image Enlarged congested liver
An enlarged congested liver can be due to rabbit haemorrhagic disease (RHD) but is also a macroscopic feature of other conditions, such as congestive heart failure or septicaemia. Close inspection of the liver shows a mottled appearance, which is suggestive of RHD. In this case, RHD was diagnosed from the histopathological finding of characteristic hepatocellular necrosis.
Located in Media / … / MACROSCOPIC CHANGES / LIVER
Image Octet Stream Pulmonary congestion and oedema
Pulmonary haemorrhage and oedema are features of RHD although, macroscopically, it can be difficult to differentiate agonal changes, such as alveolar collapse, congestion, and alveolar oedema from lung pathology. In this confirmed case of RHD, fibrin thrombi were seen in occasional small capillaries and venules on histopathological examination.
Located in Media / … / MACROSCOPIC CHANGES / LUNGS