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Enlarged, congested, mottled liver
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Congestion is often present in the organs of rabbits that have died from RHD and can mask other characteristic changes. The liver of this rabbit that died from RHD is congested. Close inspection shows a mottled appearance.
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MACROSCOPIC CHANGES
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LIVER
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Enlarged congested liver
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An enlarged congested liver can be due to rabbit haemorrhagic disease (RHD) but is also a macroscopic feature of other conditions, such as congestive heart failure or septicaemia. Close inspection of the liver shows a mottled appearance, which is suggestive of RHD. In this case, RHD was diagnosed from the histopathological finding of characteristic hepatocellular necrosis.
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MACROSCOPIC CHANGES
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LIVER
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Hepatic coccidiosis
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A low power view of hepatic coccidiosis. The rabbit died from RHD2 and this was a coincidental finding
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PATHOLOGY
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HISTOLOGY
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Eimeria steidae
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Hepatic coccidia obtained by a firmly-made impression with a microscope slide onto the cut surface of an affected liver. The slide was stained with RapidDiff2. The rabbit had died from RHDV2 which made an unavoidable preponderance of erythrocytes even with careful preparation (blotting) of the liver before applying the slide. Three slides were made and this, the third, was the only slide with coccidia. Success with this technique requires careful blotting of the cut surface and some pressure on the sides of the liver so that coccidia are squeezed out of the affected bile ducts.
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PATHOLOGY
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HISTOLOGY